Move a custom excel sheet to Access or Visual Basic

I have an excel spreadsheet with custom vbasic that uses SQL tables from my Website, as well as an ODBC connector for Quickbooks POS. It Updates the tables from the two sources, and for any products on my website that track inventory, updates the quantites available on our website with the on-hand quantities from the quickbooks inventory. This spreadsheet has gotten far too big, so I need to move the program to either a custom Visual Basic Program or an Microsoft access setup. There are also a few minor macros that the program runs, but they are fairly straight forward.